Anti Hbs Titer 1000 . The cornerstone of diagnosis is the direct antiglobulin test (DAT) which may be positive with anti IgG antisera (70% of all wAIHA) or anti IgG plus C at low titer Antibodydependent cellmediated cytotoxicity (ADCC) is the main driver of red blood cell (RBC) destruction occurring in the lymphoid organs and spleen Additional pathophysiologic mechanisms include.
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No HCP who have documentation of receiving a complete HepB series and who tested positive for anti HBs (defined as anti HBs of 10 mIU/mL or higher) are considered to be immune to hepatitis B Immunocompetent persons have longterm protection against HBV and do not need further testing or vaccine doses Some immunodeficient persons (including those on.
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If the postvaccination anti HBs level is high (greater than 10 mIU/mL) this is known to be protective and there is no need for further treatment and a booster shot is not recommended However if the postvaccination anti HBs titer is low or if there is no HPV vaccine available the healthcare worker should be administered hepatitis B immunoglobulin.
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The diagnosis of PBC is established when there is no extrahepatic biliary obstruction and no other comorbid disease affecting the liver present along with at least two of the following criteria 1) ALP of at least 15 times the ULN 2) presence of antimitochondrial antibodies (AMA) at a titer of 140 or higher and 3) histological evidence of the disease process69 PSC is a.
